Update News

 

Drugs A to Z

A B C D E F G HI J K L M N O PQ R S T U V WX Y
Z

Generic Name: cyanocobalamin (oral) (sye AN oh koe BAL a min)
Brand Name: B-12, B-12 Resin, Vitamin B12, Vitamin B-12

Vitamin B12 is water-soluble vitamin that is commonly found in a variety of foods such as fish, shellfish, meat, and dairy products. Vitamin B-12 is frequently used in combination with other B vitamins in a vitamin B complex formulation. Vitamin B-12 is restrained to protein in food.  Difficulty to absorb vitamin B-12 from the intestinal tract (food consumed) can be caused by a disease known as pernicious anemia. A day's supply of vitamin B-12 can be obtained by eating 1 chicken breast + 1 hard-boiled egg + 1 cup plain low-fat yogurt, or 1 cup milk + 1 cup raisin bran.

Drug Descriptions:

B12 is extremely effective Oral Anti-anemia Solution;

Vitamin B12 is important for growth, cell reproduction, blood, protein and tissue formation synthesis. Cyanocobalamin is used to treat vitamin B12 deficiency in people suffering from wounds in spinal cord, weakness, sore tongue, numbness in the arms and legs, diarrhea, anemia and other medical conditions.

Cyanocobalamin is a complex red Sparkling mixture cyanide, cobalt and occurring in liver; lack of solution in liver may cause intense anemia.

Formula of Cyanocobalamin Solution: C63H88O14N14PCo.

Cyanocobalamin solution can be found in following forms; injectable Solution, nasal gel, oral tablets, nasal spray, blend powder, under the tongue tablet, injected to muscles.

Each capsule contains:

Special Liver-Stomach Concentrate (containing Intrinsic Factor)

240mg

Vitamin B 12 (activity equivalent)

15mcg

Iron, Elemental (as Ferrous Fumarate)

110mg

Ascorbic Acid (Vitamin C)

75 mg

Folic Acid

0.5 mg

 
Including, other factors of Vitamin B Complex present in the Liver-Stomach.

Inactive Ingredients: 

D&C Red #28, FD&C Blue #1, FD&C Red #40, gelatin, magnesium stearate, povidone, silicon dioxide, sodium lauryl sulfate, starch and titanium dioxide.

Indications:

Hematinic (to increase amount of hemoglobin in blood) fixate with basic factor is effective in the treatment of anemia that responds to oral hematinic, including pernicious anemia which is a form of anemia characterized by scrape of the spinal cord, weakness, sore tongue, numbness in the arms & legs, diarrhea, other megaloblastic anemia and iron-deficiency anemia. Exhibiting healing quantities of forming blood or blood cells in body, factors that are known should be present in the recommended daily dose.

Dosage:

One capsule twice a day. (Two capsules daily create a stable response in the average case of dangerous anemia.)

Over dosage

Symptoms:

Iron intoxication, which may include paleness/colorlessness and inadequate oxygen content in blood, vomiting, Blood vomits, diarrhea, melena(bleeding in upper digestive track), shock, drowsiness, and coma.

Using guide for Cyanocobalamin:

  • Follow the procedure for implementing dosage. Avoid intake of this medicine in larger/smaller amounts or for longer period than recommended.
  • Dosage needs to be changed in case of pregnancy, or if you consume a vegetarian diet.
  • Cyanocobalamin is to be consumed with a full glass of water.
  • The sublingual tablet should be placed under your tongue where it will dissolve.
  • Avoid crushing, chewing, or breaking of an extended-released tablet.
  • To make sure of your condition with respect to Solution, blood of the patient is to be diagnosed every 3 to 6 months. This will help in determining the correct dose and how long to treatment with cyanocobalamin to be last.
  • In case of treating pernicious anemia, the solution is to be consumed on a regular basis for rest of the life. Avoiding Solution can lead to irreversible nerve damage in spinal cord.
  • Pernicious anemia could also be treated with folic acid to maintain red blood cells. However, folic acid will not treat Vitamin B12 deficiency and will fail in preventing possible damage to the spinal cord.
  • Store this Solution at room temperature. Prevent it from moisture, heat, and light.
  • Retain the missed dose of Cyanocobalamin solution, as soon as possible. In case the time for your next dose is near, skip the missed dose and move to your regular dosage cycle. Avoid using 2 doses at a time.

Supplied:

Capsule form, ruby red and blurred scarlet; available in 10 x 10 units dose packages.

Storage:

Solution should be Stored at controlled room temperature 15°-30°C (59°-86°F). Solution should be kept away from moisture.

Side Effects:

Iron in healing doses hardly produces gastrointestinal reactions, such as diarrhea or constipation. Reducing or avoiding the medical dose and including iron with meals will minimize its side effects in iron-sensitive patient. In rare instance, rashes over the skin implying allergy are noted by oral intake of liver-stomach solution. Allergic sensitization is found in both oral and injection through vein or muscle of folic acid.

Avoid usage of the solution if allergic to cobalt, or suffering from Leber's (abnormality of the nervous system) disease. Cyanocobalamin can lead to damage in eye/vision nerve (and possibly blindness) in people with Leber's disease.

Accidental overdose of iron-containing products is a main cause of fatal poisoning in children less than 6yrs of their age. Keep this product out of the reach of children.

Precautions

General:

Anemia requires appropriate investigation to determine its cause or causes. Folic acid alone is baseless in the treatment of vitamin B12 (liver-stomach concentrate with elemental factor) deficiency states, such as deadly anemia. Avoid consumption of alcohol while getting treated with Cyanocobalamin.

Systematic plan fits all cases, and the condition of the patient observed in follow-up is the final criterion for competence of therapy. Regular clinical and laboratory studies are must and recommended.

Pediatric Use: Dangerous and harmful for the children below 10yrs of age.

Treatment:

Solution is used for specific therapy like, exchange transfusion (replacement of patient blood with donor’s blood) and chelating agents (used to trap or remove heavy metals from bloodstream of patient).